If you open Itunes and to the left of the play bar, select the regular speakers and not the headset. This stopped auto-start for me with up to date OS and Itunes (October 2017) and Plantronics Backbeat pro 2 headset. Finding the location and format of your Apple Music/iTunes files. The Apple Music/iTunes Library is not a collection of actual files, but a collection of links to the actual physical location of the files on your hard drive. To view the actual location of your Apple Music/iTunes files and what format they are in: Right click or control-click.
1 - Fix iTunes Won't Open on Windows 10/8/7/XP etc.
Q: iTunes won't open on my Windows PC! When I press 'Ctrl-Alt-Del'and open Windows Task Manager, I can see iTunes running under 'Processes', but the program itself never appears... I've tried reinstalling and PC rebooting, nothing works. What should I do?
Solutions:
● End all iTunes related processes in Windows Task Manager and reopen iTunes. (If it fails, try removing the SC Info foler).
● Restart Windows based PC or laptop and then open iTunes at several minutes after all programs are fully loaded.
● Open iTunes by right clicking (not double clicking) the icon and 'Run as administrator'.
● Open iTunes in safe mode by pressing Ctrl + Shift, or with anti-virus software, firewall and Internet disabled.
● Empty iTunes library file located in MusiciTunes by directly deleting or moving to other path. (If it works, do remember to rebuild the library later.)
● Update/Uninstall Quicktime or repair Quicktime by Start -> Control Panel -> Programs n Features -> Quicktime -> right click to choose ('Change' and then) 'Repair'. (for Windows 7/XP/Vista)
● Remove iTunes and all of its residual components, and then do a clean reinstallation. >>Check all iTunes components
● Do the system restore.
Sometimes iTunes not opening happens with 'Cannot Open iTunes' error message of 'another user has it open' showing up. In this case, you should make sure the iTunes opened in other profile is closed, and only have one profile to start iTunes at a time.
Itunes Not Opening Macos Sierra
Also read: 5 Most Common iTunes Errors on Windows 10